Neutralization of Human Immunodeficiency Virus Type 1 by Antibody to gp120 Is Determined Primarily by Occupancy of Sites on the Virion Irrespective of Epitope Specificity

We investigated the relative importance of binding site occupancy and epitope specificity in antibody neutralization of human immunodeficiency virus (HIV) type 1 (HIV-1). The neutralization of a T-cell-line-adapted HIV-1 isolate (MN) was analyzed with a number of monovalent recombinant Fab fragments...

पूर्ण विवरण

ग्रंथसूची विवरण

में प्रकाशित:	J Virol
मुख्य लेखकों:	Parren, Paul W. H. I., Mondor, Isabelle, Naniche, Denise, Ditzel, Henrik J., Klasse, P. J., Burton, Dennis R., Sattentau, Quentin J.
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	American Society for Microbiology (ASM) 1998
विषय:	Viral Pathogenesis and Immunity
ऑनलाइन पहुंच:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109569/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9557629/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.5.3512-3519.1998
टैग:	टैग जोड़ें कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!