Identification of Determinants on a Dualtropic Human Immunodeficiency Virus Type 1 Envelope Glycoprotein That Confer Usage of CXCR4

The chemokine receptors CCR5 and CXCR4, in combination with CD4, mediate cellular entry of macrophage-tropic (M-tropic) and T-cell-tropic strains of human immunodeficiency virus type 1 (HIV-1), respectively, while dualtropic viruses can use either receptor. We have constructed a panel of chimeric vi...

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Main Authors: Cho, Michael W., Lee, Myung K., Carney, Michelle C., Berson, Joanne F., Doms, Robert W., Martin, Malcolm A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC109554/
https://ncbi.nlm.nih.gov/pubmed/9499115
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