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Spontaneous and Engineered Deletions in the 3′ Noncoding Region of Tick-Borne Encephalitis Virus: Construction of Highly Attenuated Mutants of a Flavivirus

The flavivirus genome is a positive-strand RNA molecule containing a single long open reading frame flanked by noncoding regions (NCR) that mediate crucial processes of the viral life cycle. The 3′ NCR of tick-borne encephalitis (TBE) virus can be divided into a variable region that is highly hetero...

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書誌詳細
主要な著者: Mandl, Christian W., Holzmann, Heidemarie, Meixner, Tamara, Rauscher, Susanne, Stadler, Peter F., Allison, Steven L., Heinz, Franz X.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC109508/
https://ncbi.nlm.nih.gov/pubmed/9499069
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