Spontaneous and Engineered Deletions in the 3′ Noncoding Region of Tick-Borne Encephalitis Virus: Construction of Highly Attenuated Mutants of a Flavivirus
The flavivirus genome is a positive-strand RNA molecule containing a single long open reading frame flanked by noncoding regions (NCR) that mediate crucial processes of the viral life cycle. The 3′ NCR of tick-borne encephalitis (TBE) virus can be divided into a variable region that is highly hetero...
Guardat en:
| Publicat a: | J Virol |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1998
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109508/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9499069/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.3.2132-2140.1998 |
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