A Peptide Mimic of a Protective Epitope of Respiratory Syncytial Virus Selected from a Combinatorial Library Induces Virus-Neutralizing Antibodies and Reduces Viral Load In Vivo

Respiratory syncytial virus (RSV) is the most important cause of bronchiolitis and pneumonia in infants and young children worldwide. As yet, there is no effective vaccine against RSV infection, and previous attempts to develop a formalin-inactivated vaccine resulted in exacerbated disease in recipi...

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Autores principales: Chargelegue, Daniel, Obeid, Obeid E., Hsu, Shiou-Chih, Shaw, Michael D., Denbury, Andrew N., Taylor, Geraldine, Steward, Michael W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1998
Materias:
Viral Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC109497/
https://ncbi.nlm.nih.gov/pubmed/9499058
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