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Clearance of an Influenza A Virus by CD4(+) T Cells Is Inefficient in the Absence of B Cells

The primary CD8(+) T-cell response protected most B-cell-deficient μMT mice against intranasal infection with the HKx31 influenza A virus. Prior exposure did not prevent reinfection upon homologous challenge, and the recall CD8(+) T-cell response cleared the virus from the lung within 7 days. Deplet...

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Pubblicato in:J Virol
Autori principali: Topham, David J., Doherty, Peter C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109454/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9420305/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.1.882-885.1998
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