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Strain-Dependent Myeloid Hyperplasia, Growth Deficiency, and Accelerated Cell Cycle in Mice Lacking the Rb-Related p107 Gene

To investigate the function of the Rb-related p107 gene, a null mutation in p107 was introduced into the germ line of mice and bred into a BALB/cJ genetic background. Mice lacking p107 were viable and fertile but displayed impaired growth, reaching about 50% of normal weight by 21 days of age. Mutan...

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Detalhes bibliográficos
Main Authors: LeCouter, Jennifer E., Kablar, Boris, Hardy, W. Rodney, Ying, Chuyan, Megeney, Lynn A., May, Linda L., Rudnicki, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109326/
https://ncbi.nlm.nih.gov/pubmed/9819431
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