Strain-Dependent Myeloid Hyperplasia, Growth Deficiency, and Accelerated Cell Cycle in Mice Lacking the Rb-Related p107 Gene

To investigate the function of the Rb-related p107 gene, a null mutation in p107 was introduced into the germ line of mice and bred into a BALB/cJ genetic background. Mice lacking p107 were viable and fertile but displayed impaired growth, reaching about 50% of normal weight by 21 days of age. Mutan...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	LeCouter, Jennifer E., Kablar, Boris, Hardy, W. Rodney, Ying, Chuyan, Megeney, Lynn A., May, Linda L., Rudnicki, Michael A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1998
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109326/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9819431/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.12.7455
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