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Aberrant Recruitment of the Nuclear Receptor Corepressor-Histone Deacetylase Complex by the Acute Myeloid Leukemia Fusion Partner ETO

Nuclear receptor corepressor (CoR)-histone deacetylase (HDAC) complex recruitment is indispensable for the biological activities of the retinoic acid receptor fusion proteins of acute promyelocytic leukemias. We report here that ETO (eight-twenty-one or MTG8), which is fused to the acute myelogenous...

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Autors principals: Gelmetti, Vania, Zhang, Jinsong, Fanelli, Mirco, Minucci, Saverio, Pelicci, Pier Giuseppe, Lazar, Mitchell A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC109300/
https://ncbi.nlm.nih.gov/pubmed/9819405
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