Glycogen Synthase Kinase 3β and Extracellular Signal-Regulated Kinase Inactivate Heat Shock Transcription Factor 1 by Facilitating the Disappearance of Transcriptionally Active Granules after Heat Shock

Heat shock transcription factor 1 (HSF-1) activates the transcription of heat shock genes in eukaryotes. Under normal physiological growth conditions, HSF-1 is a monomer. Its transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF-1 forms trimers, acquires DNA bin...

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Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	He, Bin, Meng, Yong-Hong, Mivechi, Nahid F.
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 1998
Subjects:	Transcriptional Regulation
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109247/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9774677/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.11.6624
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