Glycogen Synthase Kinase 3β and Extracellular Signal-Regulated Kinase Inactivate Heat Shock Transcription Factor 1 by Facilitating the Disappearance of Transcriptionally Active Granules after Heat Shock

Heat shock transcription factor 1 (HSF-1) activates the transcription of heat shock genes in eukaryotes. Under normal physiological growth conditions, HSF-1 is a monomer. Its transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF-1 forms trimers, acquires DNA bin...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	He, Bin, Meng, Yong-Hong, Mivechi, Nahid F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1998
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109247/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9774677/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.11.6624
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