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Regulation of Exit from Quiescence by p27 and Cyclin D1-CDK4

The synthesis of cyclin D1 and its assembly with cyclin-dependent kinase 4 (CDK4) to form an active complex is a rate-limiting step in progression through the G(1) phase of the cell cycle. Using an activated allele of mitogen-activated protein kinase kinase 1 (MEK1), we show that this kinase plays a...

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Detalles Bibliográficos
Main Authors: Ladha, Mohamed H., Lee, Kwang Y., Upton, Todd M., Reed, Michael F., Ewen, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC109245/
https://ncbi.nlm.nih.gov/pubmed/9774675
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