Regulation of Exit from Quiescence by p27 and Cyclin D1-CDK4

The synthesis of cyclin D1 and its assembly with cyclin-dependent kinase 4 (CDK4) to form an active complex is a rate-limiting step in progression through the G(1) phase of the cell cycle. Using an activated allele of mitogen-activated protein kinase kinase 1 (MEK1), we show that this kinase plays a...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Ladha, Mohamed H., Lee, Kwang Y., Upton, Todd M., Reed, Michael F., Ewen, Mark E.
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1998
Sujets:	Cell Growth and Development
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109245/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9774675/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.11.6605
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