The third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix both for DNA and protein interactions

The transcription factor Pax6 is essential for the development of the eyes and the central nervous system of vertebrates and invertebrates. Pax6 contains two DNA-binding domains; an N-terminal paired domain and a centrally located homeodomain. We have previously shown that the vertebrate paired-less...

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Main Authors: Bruun, Jack-Ansgar, Thomassen, Ernst Ivan Simon, Kristiansen, Kurt, Tylden, Garth, Holm, Turid, Mikkola, Ingvild, Bjørkøy, Geir, Johansen, Terje
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2005
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1092277/
https://ncbi.nlm.nih.gov/pubmed/15886395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki562
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