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Sp1-Mediated Transcription of the Werner Helicase Gene Is Modulated by Rb and p53

The regulation of Werner’s syndrome gene (WRN) expression was studied by characterizing the cis-regulatory elements in the promoter region and the trans-activating factors that bind to them. First, we defined the transcription initiation sites and the sequence of the 5′ upstream region (2.8 kb) of W...

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Udgivet i:Mol Cell Biol
Principais autores: Yamabe, Yukako, Shimamoto, Akira, Goto, Makoto, Yokota, Jun, Sugawara, Minoru, Furuichi, Yasuhiro
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1998
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109206/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9774636/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.11.6191
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