Sp1-Mediated Transcription of the Werner Helicase Gene Is Modulated by Rb and p53

The regulation of Werner’s syndrome gene (WRN) expression was studied by characterizing the cis-regulatory elements in the promoter region and the trans-activating factors that bind to them. First, we defined the transcription initiation sites and the sequence of the 5′ upstream region (2.8 kb) of W...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Yamabe, Yukako, Shimamoto, Akira, Goto, Makoto, Yokota, Jun, Sugawara, Minoru, Furuichi, Yasuhiro
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1998
Schlagworte:	Transcriptional Regulation
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109206/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9774636/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.11.6191
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