Sp1-Mediated Transcription of the Werner Helicase Gene Is Modulated by Rb and p53

The regulation of Werner’s syndrome gene (WRN) expression was studied by characterizing the cis-regulatory elements in the promoter region and the trans-activating factors that bind to them. First, we defined the transcription initiation sites and the sequence of the 5′ upstream region (2.8 kb) of W...

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Bibliographic Details
Main Authors: Yamabe, Yukako, Shimamoto, Akira, Goto, Makoto, Yokota, Jun, Sugawara, Minoru, Furuichi, Yasuhiro
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109206/
https://ncbi.nlm.nih.gov/pubmed/9774636
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