Replication-Defective Adenovirus Serotype 5 Vectors Elicit Durable Cellular and Humoral Immune Responses in Nonhuman Primates

The magnitude and durability of immune responses induced by replication-defective adenovirus serotype 5 (ADV5) vector-based vaccines were evaluated in the simian-human immunodeficiency virus/rhesus monkey model. A single inoculation of recombinant ADV5 vector constructs induced cellular and humoral...

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Autors principals: Santra, Sampa, Seaman, Michael S., Xu, Ling, Barouch, Dan H., Lord, Carol I., Lifton, Michelle A., Gorgone, Darci A., Beaudry, Kristin R., Svehla, Krisha, Welcher, Brent, Chakrabarti, Bimal K., Huang, Yue, Yang, Zhi-Yong, Mascola, John R., Nabel, Gary J., Letvin, Norman L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1091731/
https://ncbi.nlm.nih.gov/pubmed/15858035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.10.6516-6522.2005
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