Id2 Promotes Apoptosis by a Novel Mechanism Independent of Dimerization to Basic Helix-Loop-Helix Factors

Members of the helix-loop-helix (HLH) family of Id proteins have demonstrated roles in the regulation of differentiation and cell proliferation. Id proteins inhibit differentiation by HLH-mediated heterodimerization with basic HLH transcription factors. This blocks their sequence-specific binding to...

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Bibliographic Details
Main Authors: Florio, Monica, Hernandez, Maria-Clemencia, Yang, Hui, Shu, Hui-Kuo, Cleveland, John L., Israel, Mark A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109128/
https://ncbi.nlm.nih.gov/pubmed/9710627
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