Disruption of Higher-Order Folding by Core Histone Acetylation Dramatically Enhances Transcription of Nucleosomal Arrays by RNA Polymerase III

We have examined the effects of core histone acetylation on the transcriptional activity and higher-order folding of defined 12-mer nucleosomal arrays. Purified HeLa core histone octamers containing an average of 2, 6, or 12 acetates per octamer (8, 23, or 46% maximal site occupancy, respectively) w...

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Xehetasun bibliografikoak

Argitaratua izan da:	Mol Cell Biol
Egile Nagusiak:	Tse, Christin, Sera, Takashi, Wolffe, Alan P., Hansen, Jeffrey C.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Taylor & Francis 1998
Gaiak:	Transcriptional Regulation
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109049/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9671473/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.8.4629
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