Disruption of Higher-Order Folding by Core Histone Acetylation Dramatically Enhances Transcription of Nucleosomal Arrays by RNA Polymerase III

We have examined the effects of core histone acetylation on the transcriptional activity and higher-order folding of defined 12-mer nucleosomal arrays. Purified HeLa core histone octamers containing an average of 2, 6, or 12 acetates per octamer (8, 23, or 46% maximal site occupancy, respectively) w...

詳細記述

書誌詳細

出版年:	Mol Cell Biol
主要な著者:	Tse, Christin, Sera, Takashi, Wolffe, Alan P., Hansen, Jeffrey C.
フォーマット:	Artigo
言語:	Inglês
出版事項:	Taylor & Francis 1998
主題:	Transcriptional Regulation
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109049/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9671473/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.8.4629
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