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Cyclin E Associates with Components of the Pre-mRNA Splicing Machinery in Mammalian Cells

Cyclin E-cdk2 is a critical regulator of cell cycle progression from G(1) into S phase in mammalian cells. Despite this important function little is known about the downstream targets of this cyclin-kinase complex. Here we have identified components of the pre-mRNA processing machinery as potential...

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Detalles Bibliográficos
Main Authors: Seghezzi, Wolfgang, Chua, Katrin, Shanahan, Frances, Gozani, Or, Reed, Robin, Lees, Emma
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC109038/
https://ncbi.nlm.nih.gov/pubmed/9671462
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