Cytoplasmic Sequestration of the Polyomavirus Enhancer Binding Protein 2 (PEBP2)/Core Binding Factor α (CBFα) Subunit by the Leukemia-Related PEBP2/CBFβ-SMMHC Fusion Protein Inhibits PEBP2/CBF-Mediated Transactivation

The polyomavirus enhancer binding protein 2 (PEBP2)/core binding factor (CBF) is a transcription factor composed of two subunits, α and β. The gene encoding the β subunit is disrupted by inv(16), resulting in the formation of a chimeric protein, β-SMMHC, which is associated with acute myelogenous le...

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Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Kanno, Yuka, Kanno, Tomohiko, Sakakura, Chohei, Bae, Suk-Chul, Ito, Yoshiaki
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 1998
Subjects:	Transcriptional Regulation
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109009/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9632809/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.7.4252
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