DNA-Dependent Protein Kinase Phosphorylation of IκBα and IκBβ Regulates NF-κB DNA Binding Properties

Regulation of the IκBα and IκBβ proteins is critical for modulating NF-κB-directed gene expression. Both IκBα and IκBβ are substrates for cellular kinases that phosphorylate the amino and carboxy termini of these proteins and regulate their function. In this study, we utilized a biochemical fraction...

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Main Authors: Liu, Li, Kwak, Youn-Tae, Bex, Françoise, García-Martínez, León F., Li, Xiao-Hua, Meek, Katheryn, Lane, William S., Gaynor, Richard B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109006/
https://ncbi.nlm.nih.gov/pubmed/9632806
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