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Regulation of Transcription by Hypoxia Requires a Multiprotein Complex That Includes Hypoxia-Inducible Factor 1, an Adjacent Transcription Factor, and p300/CREB Binding Protein

Molecular adaptation to hypoxia depends on the binding of hypoxia-inducible factor 1 (HIF-1) to cognate response elements in oxygen-regulated genes. In addition, adjacent sequences are required for hypoxia-inducible transcription. To investigate the mechanism of interaction between these cis-acting...

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Publicat a:Mol Cell Biol
Autors principals: Ebert, Benjamin L., Bunn, H. Franklin
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108993/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9632793/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.7.4089
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