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p300-Mediated Tax Transactivation from Recombinant Chromatin: Histone Tail Deletion Mimics Coactivator Function

Efficient transcription of the human T-cell leukemia virus type 1 (HTLV-1) genome requires Tax, a virally encoded oncogenic transcription factor, in complex with the cellular transcription factor CREB and the coactivators p300/CBP. To examine Tax transactivation in vitro, we used a chromatin assembl...

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Bibliografiske detaljer
Main Authors: Georges, Sara A., Kraus, W. Lee, Luger, Karolin, Nyborg, Jennifer K., Laybourn, Paul J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC134225/
https://ncbi.nlm.nih.gov/pubmed/11739728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.1.127-137.2002
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