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Identification of Major Binding Proteins and Substrates for the SH2-Containing Protein Tyrosine Phosphatase SHP-1 in Macrophages

The protein tyrosine phosphatase SHP-1 is a critical regulator of macrophage biology, but its detailed mechanism of action remains largely undefined. SHP-1 associates with a 130-kDa tyrosyl-phosphorylated species (P130) in macrophages, suggesting that P130 might be an SHP-1 regulator and/or substrat...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Timms, John F., Carlberg, Kristen, Gu, Haihua, Chen, Haiyan, Kamatkar, Shubhangi, Nadler, Monica J. S., Rohrschneider, Larry R., Neel, Benjamin G.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108968/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9632768/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.7.3838
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