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I-SceI-Induced Gene Replacement at a Natural Locus in Embryonic Stem Cells

Gene targeting is a very powerful tool for studying mammalian development and physiology and for creating models of human diseases. In many instances, however, it is desirable to study different modifications of a target gene, but this is limited by the generally low frequency of homologous recombin...

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Bibliografske podrobnosti
Main Authors: Cohen-Tannoudji, Michel, Robine, Sylvie, Choulika, André, Pinto, Daniel, El Marjou, Fatima, Babinet, Charles, Louvard, Daniel, Jaisser, Frédéric
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC108858/
https://ncbi.nlm.nih.gov/pubmed/9488460
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