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The thymus and central tolerance.
T-cell differentiation in the thymus generates a peripheral repertoire of mature T cells that mounts strong responses to foreign antigens but is largely unresponsive to self-antigens. This state of specific immunological tolerance to self-components involves both central and peripheral mechanisms. H...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2001
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1088448/ https://ncbi.nlm.nih.gov/pubmed/11375064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2001.0846 |
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