Redefining thymus medulla specialization for central tolerance

During αβT cell development, the thymus medulla represents an essential microenvironment for T cell tolerance. This functional specialization is attributed to its typical organized topology consisting of a branching structure that contains medullary thymic epithelial cell (mTEC) networks to support...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Exp Med
Autori principali: Cosway, Emilie J., Lucas, Beth, James, Kieran D., Parnell, Sonia M., Carvalho-Gaspar, Manuela, White, Andrea J., Tumanov, Alexei V., Jenkinson, William E., Anderson, Graham
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2017
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679166/
https://ncbi.nlm.nih.gov/pubmed/28830910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171000
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