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Redefining thymus medulla specialization for central tolerance
During αβT cell development, the thymus medulla represents an essential microenvironment for T cell tolerance. This functional specialization is attributed to its typical organized topology consisting of a branching structure that contains medullary thymic epithelial cell (mTEC) networks to support...
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| Veröffentlicht in: | J Exp Med |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5679166/ https://ncbi.nlm.nih.gov/pubmed/28830910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171000 |
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