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Negative Selection in the Thymus Includes Semimature T Cells

The thymic medulla plays a key role in negative selection (self-tolerance induction) and contains differentiated T cells en route to the extrathymic environment. However, being relatively mature, medullary T cells are thought to be beyond the stage of tolerance induction. This paradox is resolved by...

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Autores principales: Kishimoto, Hidehiro, Sprent, Jonathan
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196120/
https://ncbi.nlm.nih.gov/pubmed/9016875
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