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The molecular biology of prion propagation.
Prion diseases such as Creutzfeldt-Jakob disease (CJD) in humans and scrapie and bovine spongiform encephalopathy (BSE) in animals are associated with the accumulation in affected brains of a conformational isomer (PrP(Sc)) of host-derived prion protein (PrP(C)). According to the protein-only hypoth...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1088424/ https://ncbi.nlm.nih.gov/pubmed/11260799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2000.0764 |
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