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The molecular biology of prion propagation.

Prion diseases such as Creutzfeldt-Jakob disease (CJD) in humans and scrapie and bovine spongiform encephalopathy (BSE) in animals are associated with the accumulation in affected brains of a conformational isomer (PrP(Sc)) of host-derived prion protein (PrP(C)). According to the protein-only hypoth...

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Detalhes bibliográficos
Main Authors: Clarke, A R, Jackson, G S, Collinge, J
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1088424/
https://ncbi.nlm.nih.gov/pubmed/11260799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2000.0764
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