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Using independent open-to-closed transitions to simplify aggregated Markov models of ion channel gating kinetics
Deducing plausible reaction schemes from single-channel current traces is time-consuming and difficult. The goal is to find the simplest scheme that fits the data, but there are many ways to connect even a small number of states (>2 million schemes with four open and four closed states). Many sch...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1088360/ https://ncbi.nlm.nih.gov/pubmed/15843461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409110102 |
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