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Emergence of ion channel modal gating from independent subunit kinetics

Many ion channels exhibit a slow stochastic switching between distinct modes of gating activity. This feature of channel behavior has pronounced implications for the dynamics of ionic currents and the signaling pathways that they regulate. A canonical example is the inositol 1,4,5-trisphosphate rece...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bicknell, Brendan A., Goodhill, Geoffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018786/
https://ncbi.nlm.nih.gov/pubmed/27551100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604090113
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