Ligand-induced dimerization of Drosophila peptidoglycan recognition proteins in vitro

Drosophila knockout mutants have placed peptidoglycan recognition proteins (PGRPs) in the two major pathways controlling immune gene expression. We now examine PGRP affinities for peptidoglycan. PGRP-SA and PGRP-LCx are bona fide pattern recognition receptors, and PGRP-SA, the peptidoglycan receptor...

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Autori principali: Mellroth, Peter, Karlsson, Jenny, Håkansson, Janet, Schultz, Niklas, Goldman, William E., Steiner, Håkan
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1088352/
https://ncbi.nlm.nih.gov/pubmed/15843462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407559102
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