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Ligand-induced dimerization of Drosophila peptidoglycan recognition proteins in vitro

Drosophila knockout mutants have placed peptidoglycan recognition proteins (PGRPs) in the two major pathways controlling immune gene expression. We now examine PGRP affinities for peptidoglycan. PGRP-SA and PGRP-LCx are bona fide pattern recognition receptors, and PGRP-SA, the peptidoglycan receptor...

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Detalhes bibliográficos
Main Authors: Mellroth, Peter, Karlsson, Jenny, Håkansson, Janet, Schultz, Niklas, Goldman, William E., Steiner, Håkan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1088352/
https://ncbi.nlm.nih.gov/pubmed/15843462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407559102
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