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Replication Errors during In Vivo Ty1 Transposition Are Linked to Heterogeneous RNase H Cleavage Sites

We previously identified a mutational hotspot upstream of the Ty1 U5-primer binding site (PBS) border and proposed a novel mechanism to account for this phenomenon during Ty1 replication. In this report, we verify key points of our model and show that in vivo RNase H cleavage of Ty1 RNA during minus...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mules, Emilie H., Uzun, Ozcan, Gabriel, Abram
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 1998
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC108822/
https://ncbi.nlm.nih.gov/pubmed/9448007
Tagiau: Ychwanegu Tag
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