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Replication Errors during In Vivo Ty1 Transposition Are Linked to Heterogeneous RNase H Cleavage Sites

We previously identified a mutational hotspot upstream of the Ty1 U5-primer binding site (PBS) border and proposed a novel mechanism to account for this phenomenon during Ty1 replication. In this report, we verify key points of our model and show that in vivo RNase H cleavage of Ty1 RNA during minus...

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Detalhes bibliográficos
Main Authors: Mules, Emilie H., Uzun, Ozcan, Gabriel, Abram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC108822/
https://ncbi.nlm.nih.gov/pubmed/9448007
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