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Studies on Escherichia coli RNase P RNA with Zn(2+) as the catalytic cofactor

We demonstrate, for the first time, catalysis by Escherichia coli ribonuclease P (RNase P) RNA with Zn(2+) as the sole divalent metal ion cofactor in the presence of ammonium, but not sodium or potassium salts. Hill analysis suggests a role for two or more Zn(2+) ions in catalysis. Whereas Zn(2+) de...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cuzic, Simona, Hartmann, Roland K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1088067/
https://ncbi.nlm.nih.gov/pubmed/15867194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki540
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