Activation of Protein Kinase C Triggers Its Ubiquitination and Degradation

Treatment of cells with tumor-promoting phorbol esters results in the activation but then depletion of phorbol ester-responsive protein kinase C (PKC) isoforms. The ubiquitin-proteasome pathway has been implicated in regulating the levels of many cellular proteins, including those involved in cell c...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Lu, Zhimin, Liu, David, Hornia, Armand, Devonish, Wayne, Pagano, Michele, Foster, David A.
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1998
Sujets:	Cell Growth and Development
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108795/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9447980/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.2.839
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