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Repair of cyclobutane pyrimidine dimers or dimethylsulfate damage in DNA is identical in normal or telomerase-immortalized human skin fibroblasts

The progression of a normal cell to senescence in vivo and in vitro is accompanied by a reduction in the length of the telomeres, the chromosome capping segments at the end of each linkage group. However, overexpression of the reverse transcriptase subunit (HTERT) of the ribonucleoprotein telomerase...

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Detalles Bibliográficos
Main Authors: Bates, Steven E., Zhou, Ning Ye, Federico, Laura E., Xia, Liqun, O'Connor, Timothy R.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087900/
https://ncbi.nlm.nih.gov/pubmed/15863724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki542
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