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N Terminus of Sos1 Ras Exchange Factor: Critical Roles for the Dbl and Pleckstrin Homology Domains

We have studied the functional importance of the N terminus of mouse Sos1 (mSos1), a ubiquitously expressed Ras-specific guanine nucleotide exchange factor whose C-terminal sequences bind Grb-2. Consistent with previous reports, addition of a myristoylation signal to mSos1 (MyrSos1) rendered it tran...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Autores principales: Qian, Xiaolan, Vass, William C., Papageorge, Alex G., Anborgh, Pieter H., Lowy, Douglas R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1998
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108788/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9447973/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.2.771
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