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Isocitrate Lyase (AceA) Is Required for Salmonella Persistence but Not for Acute Lethal Infection in Mice

Isocitrate lyase is required for fatty acid utilization via the glyoxylate shunt. Although isocitrate lyase is essential for Salmonella persistence during chronic infection, it is dispensable for acute lethal infection in mice. Substrate availability in the phagosome appears to evolve over time, wit...

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Bibliografski detalji
Glavni autori: Fang, Ferric C., Libby, Stephen J., Castor, Margaret E., Fung, Angela M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087437/
https://ncbi.nlm.nih.gov/pubmed/15784602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.4.2547-2549.2005
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