Mutation of Phosphotransacetylase but Not Isocitrate Lyase Reduces the Virulence of Salmonella enterica Serovar Typhimurium in Mice

A phosphotransacetylase (pta) mutant of Salmonella enterica serovar Typhimurium was attenuated in mice but survived normally in macrophages. Complementation of the pta mutation in trans restored virulence. An isocitrate lyase (aceA) mutant was virulent, so the inability to use acetate as a sole carb...

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Bibliografiske detaljer
Main Authors: Kim, Yang Re, Brinsmade, Shaun R., Yang, Zheng, Escalante-Semerena, Jorge, Fierer, Joshua
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1418904/
https://ncbi.nlm.nih.gov/pubmed/16552088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.4.2498-2502.2006
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