Isocitrate Lyase (AceA) Is Required for Salmonella Persistence but Not for Acute Lethal Infection in Mice

Isocitrate lyase is required for fatty acid utilization via the glyoxylate shunt. Although isocitrate lyase is essential for Salmonella persistence during chronic infection, it is dispensable for acute lethal infection in mice. Substrate availability in the phagosome appears to evolve over time, wit...

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Detalhes bibliográficos
Main Authors: Fang, Ferric C., Libby, Stephen J., Castor, Margaret E., Fung, Angela M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087437/
https://ncbi.nlm.nih.gov/pubmed/15784602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.4.2547-2549.2005
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