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Ionizing Radiation–dependent γ-H2AX Focus Formation Requires Ataxia Telangiectasia Mutated and Ataxia Telangiectasia Mutated and Rad3-related

The histone variant H2AX is rapidly phosphorylated at the sites of DNA double-strand breaks (DSBs). This phosphorylated H2AX (γ-H2AX) is involved in the retention of repair and signaling factor complexes at sites of DNA damage. The dependency of this phosphorylation on the various PI3K-related prote...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Friesner, Joanna D., Liu, Bo, Culligan, Kevin, Britt, Anne B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087258/
https://ncbi.nlm.nih.gov/pubmed/15772150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-10-0890
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