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Modulation of Enzymatic Activity and Biological Function of Listeria monocytogenes Broad-Range Phospholipase C by Amino Acid Substitutions and by Replacement with the Bacillus cereus Ortholog

The secreted broad-range phosphatidylcholine (PC)-preferring phospholipase C (PC-PLC) of Listeria monocytogenes plays a role in the bacterium’s ability to escape from phagosomes and spread from cell to cell. Based on comparisons with two orthologs, Clostridium perfringens α-toxin and Bacillus cereus...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Zückert, Wolfram R., Marquis, Hélène, Goldfine, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108596/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9746585/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.10.4823-4831.1998
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