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Mutagenesis of Active-Site Histidines of Listeria monocytogenes Phosphatidylinositol-Specific Phospholipase C: Effects on Enzyme Activity and Biological Function

Listeria monocytogenes, a gram-positive facultative intracellular pathogen, produces two distinct phospholipases C. PC-PLC, encoded by plcB, is a broad-range phospholipase, whereas PI-PLC, encoded by plcA, is specific for phosphatidylinositol. It was previously shown that PI-PLC plays a role in effi...

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Détails bibliographiques
Auteurs principaux: Bannam, Trudi, Goldfine, Howard
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC96294/
https://ncbi.nlm.nih.gov/pubmed/9864213
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