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Mutagenesis of Active-Site Histidines of Listeria monocytogenes Phosphatidylinositol-Specific Phospholipase C: Effects on Enzyme Activity and Biological Function

Listeria monocytogenes, a gram-positive facultative intracellular pathogen, produces two distinct phospholipases C. PC-PLC, encoded by plcB, is a broad-range phospholipase, whereas PI-PLC, encoded by plcA, is specific for phosphatidylinositol. It was previously shown that PI-PLC plays a role in effi...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Bannam, Trudi, Goldfine, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96294/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9864213/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.1.182-186.1999
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