Mutagenesis of Active-Site Histidines of Listeria monocytogenes Phosphatidylinositol-Specific Phospholipase C: Effects on Enzyme Activity and Biological Function

Listeria monocytogenes, a gram-positive facultative intracellular pathogen, produces two distinct phospholipases C. PC-PLC, encoded by plcB, is a broad-range phospholipase, whereas PI-PLC, encoded by plcA, is specific for phosphatidylinositol. It was previously shown that PI-PLC plays a role in effi...

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Podrobná bibliografie

Vydáno v:	Infect Immun
Hlavní autoři:	Bannam, Trudi, Goldfine, Howard
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1999
Témata:	Molecular and Cellular Pathogenesis
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96294/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9864213/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.1.182-186.1999
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