Increased Capacity for Interleukin-2 Synthesis Parallels Disease Progression in Mice Infected with Leishmania major

Lymph node cells of BALB/c mice with progressive leishmaniasis produced sixfold more interleukin-2 (IL-2) in culture than those of healing C57BL/6 mice. IL-2 synthesis also increased in C57BL/6 mice made susceptible by IL-12 or gamma interferon deficiency. However, IL-2 mRNA levels in vivo did not r...

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Pubblicato in:	Infect Immun
Autori principali:	Heinzel, Frederick P., Rerko, Ronald M., Hujer, Andrea M., Maier, Richard A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Fungal and Parasitic Infections
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108553/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9712815/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.9.4537-4540.1998
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